The direct proximity to two of Pittsburgh’s world-class education institutions (and their historic collaboration) creates one of the best naturally occurring innovation districts in the world.


The Pittsburgh Innovation District is centered in the city’s Oakland neighborhood and bridges the gap between innovation assets from the City’s key neighborhoods, including the Strip District, Lawrenceville, East Liberty, Bakery Square, Hazelwood Green, the South Side, Uptown, Downtown, the North Side and beyond. 

A rapidly growing innovation economy is driving a construction boom at the core of the Pittsburgh Innovation District — $3.8 billion of new real estate projects are underway in and around Oakland. These investments are shaping the future of Western Pennsylvania and providing a physical foundation to some of the most exciting and influential research on the planet.

The private and public projects underway in Oakland will deliver 1.6 million square feet of office space, at least 200,000 square feet of wet lab facilities, 714,000 square feet dedicated to research and innovation, and over 500 new hotel rooms. In addition to these additions, UPMC’s three new specialty hospitals position the Pittsburgh Innovation District as a global nexus for translational science in heart and transplant surgeries, vision rehabilitation, and cancer treatment.

Looking to relocate your startup or business to Oakland? Find the right commercial space for your team here. 

Innovation Anchors


A global research powerhouse, CMU is renowned for its world-class arts, business, computing, engineering, humanities, policy and science programs.

  • #1 Computer Science Program in the world

  • #1 Robotics Engineering Program in the world

  • #1 Artificial Intelligence Program in the US


One of the oldest and most distinguished comprehensive universities in the United States, Pitt is consistently ranked among the top research universities in both domestic and international rankings.

  • Top 5 NIH Recipient

  • Top 10 Public Institution in the Country

  • Global leader in Life Science Innovation


Consistently recognized as one of the country’s top hospital systems, UPMC is a leading nationwide healthcare provider. UPMC has distinguished history of innovation and serves as the clinical anchor of the Pittsburgh Innovation District. UPMC also operates UPMC Enterprises, a health sciences entrepreneurship and investment subsidiary headquartered in Bakery Square.

A Billion Dollar R&D Hub

The Pittsburgh Innovation District generates $1.2 billion in annual research and development. This massive investment in intellectual capital manifests through several university and public/private research centers, namely:

  • Pittsburgh Super Computing Center

  • National Robotics Engineering Center (NREC)

  • Advanced Robotics manufacturing Institute (ARM)

  • UPMC Immune Transplant and Therapy Center (ITTC)

  • McGowan Institute for Regenerative Medicine

  • Pittsburgh Health Data Alliance

Many prestigious corporate innovation leaders also take advantage of Pittsburgh’s research and development strengths. The Pittsburgh Innovation District is home to Facebook, Bosch, Uber, Microsoft, Oracle, SAP, Amazon, Yelp!, ANSYS, Intel, Apple, and others.



  • More than 169,000 students attend Pittsburgh’s 35 colleges and universities

  • 50% of graduates remain in the region

  • 41,000 degrees are awarded annually

  • Pittsburgh’s 25 to 34-year-old population grew 16% from 2011 to 2016, versus a national average of 9%